American comic books are dominated by superhero fiction. I believe this stems from a combination of a lot of popular genres back in early comic namely westerns, science fiction, and mystery. Webcomics followed a different path. I may talk more about this when I get to Roomies later this month(I haven't decided yet), but for now I'll just say webcomics have more of an inspiration from comic strips found in newspapers. This means their is more of a focus on comedy then drama, and updates tend to be smaller (Comic books tend to have about 21 pages. When a webcomic updates it ranges from a panel to a page). Their maybe better examples of this but 'Two Guys and Guy' fits the description perfectly.